HAPDeNovoHAPDeNovo is a software package to detect de novo mutations on barcoded linked read sequencing. We identified the major source of de novo mutation from NGS data was caused by the biased haplotype coverage. HAPDeNovo can eliminate more than 99% false positive de novo calls with the help of 10X linked read sequencing.
For more information visit the HAPDeNovo website.
These versions of HAPDeNovo are available on the BEAR systems (BlueBEAR, BEARCloud VMs, and CaStLeS VMs). These will be retained in accordance with our Applications Support and Retention Policy.