SigProfilerMatrixGeneratorSigProfilerMatrixGenerator is a python framework that creates mutational matrices for somatic mutations. This tool works to identify and categorize the mutations based on possible single nucleotide variants (SNVs), double base substitutions (DBS), and insertions/deletions and provides further transcriptional strand bias categorization. It downsizes the generated mutations to parts of the genome like the exome or a custom BED file to help identify true mutational signatures within a genome. SigProfilerMatrixGenerator seamlessly integrates with other SigProfiler tools.
For more information visit the SigProfilerMatrixGenerator website.
These versions of SigProfilerMatrixGenerator are available on the BEAR systems (BlueBEAR, BEARCloud VMs, and CaStLeS VMs). These will be retained in accordance with our Applications Support and Retention Policy.
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